MIGU supplied Dodder Seed Extract and other standard purity and OEM service with analysis meets the EP, USP, JP, CP.....
Dodder Seed Extract 4:1 ,10:1, 20:1 by TLC offered by MIGU--a 17 years experienced cGMP manufacturer
with warehosues in NJ & CA, USA.
Latin Name: Cuscuta epithymum (L.) L
Material Original: LiaoNing, JiLin ,HeBei, China
Extracted Part: Seed
Supported Purity:5:1 10:1 20:1 30:1 40:1 50:1 and etc
The History of Dodder Seed ?
Cuscuta chinessis ( Dodder seed, also known as cuscuta seed or Tu Si Zi in mandarin) is an annual parasitic herb
It is a rootless, wholly parasitic plant that occurs most commonly on heather ( Calluna vulgaris ), gorse (Ulex
europaeus) and clover (Trifolium) species. Clover dodder is native to Europe, but occurs almost worldwide.It is
a member of the Convolvulaceae family, which includes Ipomoea and Convolvulus species, many of which are
commonly known as bindweed and morning glory. In China it is produced in provinces of Liaoning, Jilin, Hebei
Henan, Shandong, Shanxi, and Jiangsu.
How does the Dodder Seed Extract actions in pharmacological ?
Dodder Seed Extract has long been considered a fabulous mild tonic used in Chinese herbal remedies.Just as its
name implies, it comes from a parasitic plant that only survives by absorbing the essence from its host.Since
ancient herbalists found no root from dodder,they thought it had some kind of magic power.It may be for this
reason that it was listed as one of the superior herbs in the “Shen Nong’s Herbal Classic.” Being an excellent
tonic for kidney, liver, and spleen, traditionally dodder seeds, alone or in combination with other ingredients
can assist the treatment of various diseases, in particular impotence, nocturnal emission,alopecia areata
habitual abortion,visual deterioration,frequent urination,melasma,lower back pain caused by kidney deficien-
cy chyluria, infertility, fetal irritability, and more.It contains quercetin, astragalin, hyperin, and quercetin-3-O-β-D
-galactose-7-O-β-glucoside.And the fruit of C japonica also contains alkaloids.
Our Specification and Purity of Dodder Seed Extract
The benefits of Dodder Seed Extract
In traditional Chinese medicine, it is commonly used in the treatment of diseases like infertility and fetal
irritability. And in recent years a lot of progress has been made on the researches of this herb. Now, let’s take
a look at its health benefits from the angles of the results of scientific research and TCM theory.
1)Osteoporosis and alopecia, In a June 2010 article appearing in “Phytotherapy Research,” drynol cibotinis,a
newly developed botanical combination including Cuscuta chinensis was investigated for its therapeutic
benefits for treating osteoporosis. Each of the botanicals in this mixture has been used in traditional Chinese
medicine to treat osteoporosis.The researchers assessed effects of drynol cibotin on cell growth,programmed
cell death, calcium uptake and production of bone matrix proteins. The results showed that drynol cibotin
significantly increased cell proliferation and inhibited cell death in osteoblasts,
2)Alopecia, or hair loss, is an androgen-driven psychologically distressing condition,which affects millions of
men and women.In an article appearing in the September 2008 issue of the“Journal of Cosmetic Dermatology”
researchers evaluated Dodder Seed Extract reflexa for hair growth activity in test animals with alopecia.The authors used
petroleum extract of C. reflexa on albino mice with testosterone-induced alopecia for 20 days. Its inhibitory
abilities were evaluated by follicular density and microscopic observation of skin sections. The study found
that the extract exhibited promising hair growth activity as reflected in follicular density and skin section
observation. Inhibition of enzymatic activity suggested that the extract reversed androgen-induced alopecia
by inhibiting conversion of testosterone to dihydrotestosterone.
3)Male InfertilityThe March2006edition of the“Chinese Archives of Traditional Chinese Medicine”documented
the damage caused by reactive oxygen species, ROS,to human sperm and the mechanism by which Cuscuta
japonica can treat male infertility.Sperm cell with normal physiological function were selected and different
concentrations of extract were incubated with sperm in the ROS environment. The cells’ integrity was
calculated and the sperm structure was observed.The authors found that extract from C. japonica can
significantly protect the sperm cell membrane,as well as its structure and the cellular function from the
damage caused by ROS.
4)Sexual benefit for men-It’s said to increase male fertility.Recently,scientists have discovered that derived
properties of the plant can actually protect the male’s sperm.The5key active molecules that are responsible
for the function are beta-sitosterol, d-sesamin,9(R)-hydroxy-d-sesamin, d-pinoresinol and daucosterol – each
serving to protect the sperm cell membrane and mitochondrion function, preserving the sperm’s acosomic
structure and preventing damage from free radicals. But benefits to men don’t end there. Cuscuta is often
an important ingredient of erection enhancement formulas, as it helps increase production of Nitric Oxide
Syntheses inside the penile tissues. It also enhances the intra-cavernosal pressure (ICP) inside the penis
resulting in harder and fuller erection.To find out for yourself if the formulas that benefit from the inclusion
of cuscuta can have a similarly positive effect on your sexuality.
5)Other effects.Its can increase resistance to cerebral ischemia, enrich heart blood, tonify kidney enhances
immunity,Antiaging and antioxidant action,make up a deficiency,help bodybuilding,reduce urine output and
the frequency of urination, and so on.
Sample Dodder Seed Extract recipes on herbal remedies
The Chinese Materia Medica believes that seed of dodder is acrid,sweet in flavor and warm in nature.It goes
to meridians of liver,kidney, and spleen. Primary functions are nourishing kidney to strengthen the essence
nourishing liver to improve visual acuity, preventing miscarriage, and stopping diarrhea. Elementary dodder
seed uses and indications include knee and lower back pain,emission,impotence,premature ejaculation
infertility,diabetes,stranguria with turbid discharge, enuresis, blurred vision, ringing in ears, fetal irritability
abortion, and diarrhea.Recommended dodder seed dosage is from 6 to15 grams in decoction. Other relevant
products include dodder seed supplement, tea, extract,capsules,powder, and more.You can choose one of
them according to your situation.
1) Wu Zi Yan Zong Wan from Dan Xi Xin Fa (Dan Xi’s Experiential Methods).It is combined with Gou Qi Zi(Goji
Berry),FuPenZi(Raspberry fruit),Wu Wei Zi(Schisandra Seed),and Che Qian Zi(Plantain Seeds)to treat erectile
dysfunction (ED) and nocturnal emission;
2) Tu Si Zi Wan from Shi Yi De Xiao Fang (Effective Formulas from Generations of Physicians).It is formulated
with Sang Piao Xiao (Ootheca Mantidis), Rou Cong Rong (Cistanche),Deer Antler Velvet (Lu Rong),etc.to cure
excessive urination or incontinence;
3) FuLingWan from TaiPinHuiMinHeJiJuFang (Formulas of the Peaceful Benevolent Dispensary).It is matched
with FuLing(Poria)and ShiLianZi(Sinocrassula indica seed)to heal nocturnal emission,gonorrhea,and a stream
of urine dripping when peeing;
4) ZhuJingWan from HeJiJuFang.It’s joined with ShuDiHuang(Rehmannia Root)and Plantain Seed to improve
eyesight by nourishing the liver and kidney, boosting essence, and enriching blood;
5) TuSiZiWan from ShenShiZunShengShu(Master Shen’s Writings on Respecting Life).It is equipped with Goji
Berry,ShanYao (Chinese Yam) and Lian Zi (Lotus Seeds) to treat diarrhea caused by deficiency of spleen and
kidney;
6) ShouTaiWan from Yi Xue Zhong Zhong Can Xi Lu ( Records of Heart-Felt Experiences in Medicine with
Reference to the West).It works with Xu Duan (Japanese Teasel Root), SangJiSheng (Loranthus),and E Jiao
(Donkey-Hide Gelatin) to cure kidney-deficiency induced threatened abortion or habitual abortion.
Dodder Seed Extract side effects and contraindications
Dodder Seed Extract contains vitamin A, carotene, protein and other nutrients. From the perspective of TCM, it is
with no side-effects to human body. Hence, it is safe to be consumed even though in large dose. Clinically
ShenNongBen Cao Jing Shu(Commentary on‘ShenNong’s Classic of the Materia Medica)says that it shouldn’t
be used by patients with kidney problem and excessive fire, persistent penile erection, or hard, dry stools
De Pei Ben Cao ( Materia Medica of Combinations) reviews that it is inadvisable for pregnant women and
patients with profuse uterine bleeding, a prolonged erection of the penis,constipation,kidney fire,and fire
excess from Yin deficiency.More Scientific research and development , please check here
References
1) Bei Jing Zhong Yi (Beijing Chinese Medicine), 1995; (5):20;
2) He Bei Zhong Yi Za Zhi (Hebei Journal of Chinese Medicine), 1988; (5):16;
3) An Hui Dan Yan Fang Xuan Ji ( The Anthology of Proved Recipes Based on Single Ingredient in Anhui ) by
Anhui People’s Publishing House, 1972; 300.
4) Journal of Medicinal Food:Cuscuta chinensis extract promotes osteoblast differentiation& mineralization
in human osteoblast-like MG-63 cells
5) Journal of Cosmetic Dermatology: Effect of Cuscuta reflexa Roxb on androgen-induced alopecia
6) Chinese Archives of Traditional Chinese Medicine: Protection of extract from Cuscuta japonica on human
sperm acrosome and ultrastructure